Heterocyclic aldehydes such as 2-thiophenecarbaldehyde (1) condense with 3-aroylpropionic acids 2 or their sodium salts to give the enol lactones 3a-d of 3-aroyl-2-(2-thienylmethy-1ene)propionic acids. Isomerization of 3 ad leads to the corresponding 4-arylbenzo[b]thiophene-6-carboxylic acids 4a-d.
✦ LIBER ✦
Synthesis of Enol Lactones of (E)-3-aroyl-2-(5-methyl-2-furylmethylene and 5-methyl-2-thienylmethylene)propionic acids and their con-conversion into the corresponding 4-arylbenzol[b](2-methylfuran and 2-methylthiophene)-s-carboxylic acids
✍ Scribed by Dr. Nadia R. Guirguis; Boshra M. Awad; Hanaa A. Saad
- Book ID
- 105353695
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 303 KB
- Volume
- 332
- Category
- Article
- ISSN
- 1615-4150
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