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[3+2] Cycloaddition Reaction of Cyclopropyl Ketones with Alkynes Catalyzed by Nickel/Dimethylaluminum Chloride

✍ Scribed by Takashi Tamaki; Dr. Masato Ohashi; Prof. Sensuke Ogoshi


Book ID
101573060
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
310 KB
Volume
50
Category
Article
ISSN
0044-8249

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πŸ“œ SIMILAR VOLUMES


[3+2] Cycloaddition Reaction of Cyclopro
✍ Takashi Tamaki; Dr. Masato Ohashi; Prof. Sensuke Ogoshi πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 328 KB πŸ‘ 1 views

de reagents. The key to success is the organoaluminum reagents, which activate the carbonyl group of cyclopropyl ketones and stabilize the reaction intermediates. This reaction provides a new method for the synthesis of cyclopentene derivatives. Additional studies to elucidate the reaction mechanism

Halogen-dependent coupling reaction of a
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Ni-catalyzed coupling reaction of alkynes with (Z)-3-halopropenoates depended on the halogen of halopropenoates. The reaction with (Z)-3-bromopropenoate afforded cyclopentadienes and the reaction with (Z)-3-iodopropenoates gave pyrones.