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31P spectroscopy of the human prostate gland in vivo using a transrectal probe

✍ Scribed by John Kurhanewicz; Albert Thomas; Prahalad Jajodia; Michael W. Weiner; Thomas L. James; Daniel B. Vigneron; Perinchery Narayan

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
672 KB
Volume
22
Category
Article
ISSN
0740-3194

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✦ Synopsis

Abstract

Using a transrectal probe, good quality ^31^P magnetic resonance spectroscopy of the human prostate was performed safely, consistently, and in a reasonable amount of time (average of 60 min). Initial results indicate that transrectal ^31^P MRS has the ability to characterize the phosphorylated metabolites of normal, hyperplastic, and malignant prostates. This study demonstrated that malignant prostates are characterized by significantly decreased levels of phosphocreatine (PCr) and increased levels of phosphomonesters (PME) as compared to healthy prostates. Β© 1991 Academic Press, Inc.

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