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303 Hypoxic conformance of metabolism in primary rat hepatocytes: A model of hepatic hibernation

✍ Scribed by R.M. Subramanian; N. Chandel; S. Budinger; P. Schumacker

Book ID
117374582
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
252 KB
Volume
44
Category
Article
ISSN
0168-8278

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Hypoxic conformance of metabolism in pri
Hypoxic conformance of metabolism in primary rat hepatocytes: A model of hepatic hibernation
✍ Ram M. Subramanian; Navdeep Chandel; G. R. Scott Budinger; Paul T. Schumacker πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 361 KB πŸ‘ 1 views

Following prolonged hypoxia, mammalian cells invoke adaptive mechanisms to enhance oxygen delivery and promote energy conservation. We previously reported that hepatocytes subjected to prolonged moderate hypoxia (PO2 = 20-50 mmHg for > 3 hours) demonstrated a reversible inhibition of cellular respir