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3-TMS-cyclopentene-1 a new reagent for the synthesis of cyclopentene derivatives

✍ Scribed by Iwao Ojima; Miyoko Kumagai; Yuji Miyazawa

Publisher
Elsevier Science
Year
1977
Tongue
French
Weight
200 KB
Volume
18
Category
Article
ISSN
0040-4039

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✦ Synopsis

Recently, allyltrimethylsilane has been shown to be a good reagent for allylation of acyl halides 1 or carbonyl compounds 2 in the presence of Lewis acid. Now we wish to report here a new and convenient route to cyclopentene derivatives using the reactions of 3-trimethylsilylcyclopentene-1, a cyclic allylsilane, with various carbonyl compounds. 3-TMS-cyclopentene-1 is a useful new reagent for the regiospecific introduction of cyclopentene skeleton in organic synthesis, which can easily be prepared by the hydrosilylation of cyclopentadiene.

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