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3-N-(2-[18F]-fluoroethyl)-spiperone: A novel ligand for cerebral dopamine receptor studies with pet

✍ Scribed by H.H. Coenen; P. Laufer; G. Stöcklin; K. Wienhard; G. Pawlik; H.G. Böcher-Schwarz; W.-D. Heiss


Book ID
118342332
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
473 KB
Volume
40
Category
Article
ISSN
0024-3205

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## Abstract The synthesis of a tosylate precursor for the radiosynthesis of a potential PET radiotracer, (S)‐N‐[(1‐ethyl‐2‐pyrrolidinyl)methyl]‐5‐(2‐[^18^F]fluoroethyl)‐2‐ methoxybenzamide is reported. Reaction of ^18^F‐fluoride with the tosylate provides the radiolabeled product in 10–25% yield. S