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18F-desmethoxyfallypride: A fluorine-18 labeled radiotracer with properties similar to carbon-11 raclopride for pet imaging studies of dopamine D2 receptors

✍ Scribed by Jogeshwar Mukherjee; Zhi-Ying Yang; Terry Brown; James Roemer; Malcolm Cooper


Book ID
116019217
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
857 KB
Volume
59
Category
Article
ISSN
0024-3205

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## Abstract The synthesis of a tosylate precursor for the radiosynthesis of a potential PET radiotracer, (S)‐N‐[(1‐ethyl‐2‐pyrrolidinyl)methyl]‐5‐(2‐[^18^F]fluoroethyl)‐2‐ methoxybenzamide is reported. Reaction of ^18^F‐fluoride with the tosylate provides the radiolabeled product in 10–25% yield. S