Efficient Synthesis of 1,4-Thiazepin-3-o
β
Zaleska, Barbara ;CieΕΌ, Dariusz ;Grochowski, Jacek ;Serda, Pawel ;Winnik, Witold
π
Article
π
2006
π
John Wiley and Sons
π
English
β 535 KB
## Abstract A new oneβpot synthesis of title compounds 2 by reaction of Ξ²βaminothiocinnamic acid anilides 1 with Ξ±βhaloacid halides is described. The ring of 1,4βthiazepine 2 in basic medium undergoes transformation to thiazolidinβ4βones 5.