ChemInform Abstract: Stereoselective Syn
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A. POHLMANN; D. GUILLAUME; J.-C. QUIRION; H.-P. HUSSON
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Article
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2010
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John Wiley and Sons
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Stereoselective Synthesis of 1,3-Disubstituted Hexahydro-1,4diazepin-2-ones. -A fast and facile asymmetric synthesis of the title compounds (VI), a kind of constrained peptides, involving the diastereoselective alkylation of optically pure hydroxylactam (IV) as the key step is described.