1251 Amiodarone was prepared by iodination of 1 2SI 251 amiodarone was obtained 2-n butyl 4-hydroxy 3-benzoyl benzofuran with Na in alkaline medium. By amination with N8N-diethyl 2-amino 1 -chloroethane, with 30 % yield and a specific activity of about 1 Ci/mmOl.
3-aminopiperidones IV. 2-(N, N-diethylamino)-2-p-chlorophenylglutarimide and 2-(N, N-diethylamino)-2-p-tolylglutarimide
β Scribed by S. K. Arya; K'un Chang; C. F. Martin
- Publisher
- John Wiley and Sons
- Year
- 1967
- Tongue
- English
- Weight
- 417 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0022-3549
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π SIMILAR VOLUMES
The chffuslon coefficients of the metastable mtropen atoms N\*(\*D) and N\*(\*P) have been determined in pure nitroggea ~1 an afrer@o\v exwnment From the tune evolution of the metastable densmes the dlffuslon coefficients were found to bc DO = (5 2 2 0.6) x 10" and Do('D) = (6.4 = I) x lol\* atoms 0
Condsnsatwn of eodiwn monochlomcetate d 4 C with sodium p-butoqphenate : 1 i n benxene -DMF give8 rise t o radiochemically pure p-butoqphenoq acetic a~nX-l-1~C : 2 i n a 76 % yield. The latter is transformsd into ths acyt chloride 3 which with the amine 4 leads to the t i t l e d d e : 5 i n a 89 %