3-Amino- and 5-Aminopyrazoles with Anticonvulsant Activity
✍ Scribed by Hans-Joachim Lankau; Manfred Menzer; Angelika Rostock; Thomas Arnold; Chris Rundfeldt; Klaus Unverferth
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 31 KB
- Volume
- 332
- Category
- Article
- ISSN
- 0365-6233
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## Abstract Several 5‐alkoxy‐tetrazolo[1,5‐__a__]quinazoline derivatives have been synthesized by reacting 2,4‐dichloroquinazoline with various phenols or aliphatic alcohol and then with sodium azide. The structures of these compounds have been confirmed by IR, MS, ^1^H‐NMR, and elementary analysis
**Die Carbamidsäureester __(2)‐(4)__, die für biologische Untersuchungen benötigt werden**, sind nicht durch Acylierung der Amino‐triazole __(1)__ zugänglich, wie eine Reihe gescheiterter Syntheseversuche zeigt (R und R′ = Alkyl oder Aryl). Der Carbamidsäure‐Rest muß vielmehr schon bei der Synthese
systems by the single bonds C7-N2 and C8-N1. The three nitrogen-nitrogen bonds are all shorter than the usual single N-N distance of 1.44w110.' \*I, and the N2-N4 distance is only slightly longer than the 1.24A expected for a double bond['0,''! A calculation of the best leastsquares plane passing th