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Anticonvulsant activity of reaction products of 5,5-diphenylhydantoin with substituted methylene bromides

โœ Scribed by Cyril O. Usifoh


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
33 KB
Volume
334
Category
Article
ISSN
0365-6233

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A series of (S)-(+)-5-n-propyl-2-iminohydantoins with various N-1 substituents were synthesized and tested for anticonvulsant activity to better understand the structure-activity relationship (SAR) of 2-iminohydantoins. Compounds with N-1 phenoxycarbonyl (2), ethoxycarbonyl (6), t-butoxycarbonyl (7)