260p53 and p16 expression after γ-irradiation and heat treatment in human tumor cell lines
✍ Scribed by Valenzuela, M.T.; Nuñez, M.I.; Villalobos, M.; Guerrero, M.R.; Pedraza, V.; Ruiz, de Almodóvar J.M.
- Book ID
- 122088319
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 129 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0167-8140
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
To assess the potential relationship between p53 and p16 proteins in the cellular response to stress, we have examined the levels of these proteins in a series of human tumor cell lines after treatment with either ionizing radiation or hyperthermia. We found that cells with abnormal radiationinduced
The p 16INK4 tumor-suppressor gene (also known as CDKNZ, CDK41 and MTSI) encodes a negative regulator of the cell cycle. This gene, located in 9pZ I, is mutated or homozygously deleted in a high percentage of tumor cell lines and specific types of primary tumors. We have examined the status of the p