2,5-Dimethyl-4-(p-aminobenzyl)pyridine in the synthesis of substituted quinolines, pyridoindazoles, and isoquinolinoquinolines
β Scribed by N. S. Prostakov; A. P. Krapivko; A. T. Soldatenkov; N. D. Sergeeva
- Book ID
- 112370860
- Publisher
- Springer US
- Year
- 1980
- Tongue
- English
- Weight
- 375 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0009-3122
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## Abstract A new series of 2β(__p__βtolyloxy)β3β(5β(pyridinβ4βyl)β1,3,4βoxadiazolβ2βyl)quinoline were synthesized from oxidative cyclization of __N__β²β((2β(__p__βtolyloxy)quinolineβ3βyl)methylene)isonicotinohydrazide in DMSO/I~2~ at reflux condition for 3β4 h. The structures of the new compounds w
## 2-PhenyC4-p-tolylhydrazono-2-oxazoline-5-one (3) was rearranged by the action ofphenols and naphthols into 1,2,4-triazole-5-carboxylic esters (5) that were rearranged further o n reflux in AcOH-ZnCl, into triazolyl ketones (7). Rearrangement of 3 into 1,2,4-triazole derivatives could also be ef