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2.47 p53 Homolog p63 Promotes Apoptosis and Chemosensitivity in Chronic Lymphocytic Leukemia B-Cells

✍ Scribed by Ryan Collins; Prabhjot Kaur; Olga Danilova; James Direnzo; Alexey V. Danilov

Book ID
119218875
Publisher
Elsevier
Year
2011
Tongue
English
Weight
68 KB
Volume
11
Category
Article
ISSN
2152-2650

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## Abstract Signal transduction and apoptosis in B‐cell chronic lymphocytic leukemia (CLL) cells with a post‐germinal center (GC) phenotype were studied. Specific activation of the cells was induced by a combination of soluble anti‐CD40 monoclonal antibody and interleukin‐4 (CD40/IL‐4) and nonspeci