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Rapamycin and curcumin induce apoptosis in primary resting B chronic lymphocytic leukemia cells

✍ Scribed by Hayun, Rami; Okun, Eitan; Berrebi, Alain; Shvidel, Lev; Bassous, Lucette; Sredni, Benjamin; Nir, Uri

Book ID: 121185997
Publisher: Informa plc
Year: 2009
Tongue: English
Weight: 511 KB
Volume: 50
Category: Article
ISSN: 1042-8194
DOI: 10.1080/10428190902789181

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## Abstract Signal transduction and apoptosis in B‐cell chronic lymphocytic leukemia (CLL) cells with a post‐germinal center (GC) phenotype were studied. Specific activation of the cells was induced by a combination of soluble anti‐CD40 monoclonal antibody and interleukin‐4 (CD40/IL‐4) and nonspeci