2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced lipid peroxidation in genetically responsive and non-responsive mice
β Scribed by Hamid Mohammadpour; Wallace J. Murray; Sidney J. Stohs
- Publisher
- Springer
- Year
- 1988
- Tongue
- English
- Weight
- 631 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0090-4341
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The exhalation of ethane is widely used as an indicator of in vivo lipid peroxidation. To test the hypothesis that lipid peroxidative events are involved in the toxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD), we administered a lethal dose of TCDD (60 micrograms/kg), IP to male Sprague-Daw
## Abstract 2,3,7,8βTetrachlorodibenzoβ__p__βdioxin (TCDD) is a potent immunosuppressant in several animal species. The purpose of this study was to determine if TCDD affected the activity of adenosine deaminase (ADA), a purine metabolizing enzyme that is vital to the proper functioning of the immu