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2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced lipid peroxidation in genetically responsive and non-responsive mice

✍ Scribed by Hamid Mohammadpour; Wallace J. Murray; Sidney J. Stohs


Publisher
Springer
Year
1988
Tongue
English
Weight
631 KB
Volume
17
Category
Article
ISSN
0090-4341

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Absence of lipid peroxidation as determi
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The exhalation of ethane is widely used as an indicator of in vivo lipid peroxidation. To test the hypothesis that lipid peroxidative events are involved in the toxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD), we administered a lethal dose of TCDD (60 micrograms/kg), IP to male Sprague-Daw

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✍ Muralidhara, ;Matsumura, Fumio ;Blankenship, Alan πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 978 KB

## Abstract 2,3,7,8‐Tetrachlorodibenzo‐__p__‐dioxin (TCDD) is a potent immunosuppressant in several animal species. The purpose of this study was to determine if TCDD affected the activity of adenosine deaminase (ADA), a purine metabolizing enzyme that is vital to the proper functioning of the immu