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2.246 THE EFFICACY AND SAFETY OF TOLCAPONE IN PATIENTS WITH PARKINSON'S DISEASE

✍ Scribed by C. Zhang

Book ID
117754939
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
51 KB
Volume
18
Category
Article
ISSN
1353-8020

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## Abstract Tolcapone is a potent, reversible catechol‐O‐methyltransferase (COMT) inhibitor with both peripheral and central activity. It has been demonstrated to improve motor function and allow levodopa dose reductions in Parkinson's disease (PD) patients who are experiencing either a stable resp