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210: Effect of sesamin, sesamolin and sesamol on P-glycoprotein mediated efflux

โœ Scribed by Junhom, C.; Siriwarin, B.; Weerapreeyakul, N.; Barusrux, S.

Book ID
125802997
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
68 KB
Volume
50
Category
Article
ISSN
0959-8049

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โœ Yukiko Akazawa; Hiroko Kawaguchi; Maki Funahashi; Yoshihiko Watanabe; Kiyoshi Ya ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 139 KB

The effect of interferon (IFN)-beta and IFN-gamma on P-glycoprotein (P-gp)-mediated efflux of rhodamin-123(Rho-123), a typical substrate of P-gp, was studied in rat hepatocytes in primary culture. After treatment with IFN-beta, IFN-gamma, or both for 3 days, steady-state levels of Rho-123, incorpora