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2-Substituted derivatives of 9-.alpha.-D-arabinofuranosyladenine and 9-.alpha.-D-arabinofuranosyl-8-azaadenine

✍ Scribed by Montgomery, John A.; Shortnacy, Anita T.; Arnett, G.; Shannon, W. M.


Book ID
125517479
Publisher
American Chemical Society
Year
1977
Tongue
English
Weight
576 KB
Volume
20
Category
Article
ISSN
0022-2623

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## Abstract The anticancer effects of 9‐β‐(2′‐azido‐2′‐deoxy‐D‐arabinofuranosyl)adenine (arazide) were compared to those of 9‐β‐D‐arabinofuranosyladenine (araA) in P388 leukemia cells. Arazide was less susceptible than araA to deamination by a partially purified preparation of adenosine deaminase f