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2-Methoxyestradiol induces mitochondria dependent apoptotic signaling in pancreatic cancer cells

✍ Scribed by Qanungo, Suparna; Basu, Aruna; Das, Madhusudan; Haldar, Subrata


Book ID
110066696
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
318 KB
Volume
21
Category
Article
ISSN
0950-9232

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## Abstract The anti‐cancer potential of the natural estrogen metabolite 2‐methoxyestradiol is associated with microtubuli interaction, anti‐angiogenetic effects and inhibition of superoxide dismutase leading to apoptosis. The effectors of apoptotic signaling through 2‐methoxyestradiol, however, ar