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2-Chloroacetaldehyde: a metabolite of cyclophosphamide in the rat

✍ Scribed by Shaw, I.C.; Graham, M.I.; McLean, A.E.M.


Book ID
122562675
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
691 KB
Volume
10
Category
Article
ISSN
0305-7372

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Alcophosphamide was identified in urine obtained from Sprague-Dawley rats treated with a 1 : l mixture of cyclophosphamide and f3-(2H4)cyclophosphamide using chemical ionization mass spectrometry and the ion cluster technique. This compound was also quantified in rat plasma using gas chromatographic