𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Pharmacokinetics of N-2-chloroethylaziridine, a volatile cytotoxic metabolite of cyclophosphamide, in the rat

✍ Scribed by Hong Lu; Kenneth K. Chan

Publisher
Springer
Year
2006
Tongue
English
Weight
282 KB
Volume
58
Category
Article
ISSN
0344-5704

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Stereoselective pharmacokinetics of desb
Stereoselective pharmacokinetics of desbutylhalofantrine, a metabolite of halofantrine, in the rat after administration of the racemic metabolite or parent drug
✍ Dion R. Brocks πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 114 KB πŸ‘ 1 views

## Abstract The main objective of this study was to determine the pharmacokinetics of the enantiomers of desbutylhalofantrine (DHF), a metabolite of halofantrine (HF), in the rat. Rats received either intravenous (2 mg/kg) or oral (7 mg/kg) (Β±)‐DHF HCl, or (Β±)‐HF HCl intravenously (3 mg/kg). Enanti

Identification and quantitation of alcop
Identification and quantitation of alcophosphamide, a metabolite of cyclophosphamide, in the rat using chemical ionization mass spectrometry
✍ Phillip S. Hong; Kenneth K. Chan πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 505 KB

Alcophosphamide was identified in urine obtained from Sprague-Dawley rats treated with a 1 : l mixture of cyclophosphamide and f3-(2H4)cyclophosphamide using chemical ionization mass spectrometry and the ion cluster technique. This compound was also quantified in rat plasma using gas chromatographic