𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Determination of chloroacetaldehyde, a metabolite of oxazaphosphorine cytostatic drugs, in plasma

✍ Scribed by G.P. Kaijser; J.H. Beijnen; E.L. Jeunink; A. Bult; H.J. Keizer; J. de Kraker; W.J.M. Underberg

Book ID
103804654
Publisher
Elsevier Science
Year
1993
Weight
497 KB
Volume
614
Category
Article
ISSN
0378-4347

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

High-Performance Liquid Chromatographic–
High-Performance Liquid Chromatographic–Fluorescent Method to Determine Chloroacetaldehyde, a Neurotoxic Metabolite of the Anticancer Drug Ifosfamide, in Plasma and in Liver Microsomal Incubations
✍ Zeqi Huang; David J. Waxman πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 English βš– 105 KB

Chloroacetaldehyde (CA) is a nephrotoxic and neurotoxic metabolite of the anticancer drug ifosfamide (IFA) and is a dose-limiting factor in IFA-based chemotherapy. Plasma levels of CA in IFA-treated cancer patients are often difficult to determine due to the lack of a sufficiently sensitive and spec

Determination of oxycodone in plasma and
Determination of oxycodone in plasma and identification of a major metabolite
✍ Stephen H. Weinstein; Janet C. Gaylord πŸ“‚ Article πŸ“… 1979 πŸ› John Wiley and Sons 🌐 English βš– 268 KB

An electron-capture GLC method is described for oxycodone and its major metabolite, noroxycodone, in plasma and urine. The method involves extraction of the two substances into benzene-isopropranol at pH 10.4, followed by back-extraction into 0.1 N HCl. The acid phase is washed with hexane and made