2-Amino-4-aryl-6-(ω-carboxyalkyl)-5H-pyrrolo[3,4-d]pyrimidin-7-(6H)ones. Preparation via a one-pot synthesis of 1-(ω-carboxyalkyl)-4-carbethoxy-2,3-dioxopyrrolidines
✍ Scribed by R. Madhav; Carroll A. Snyder; Philip L. Southwick
- Book ID
- 112126147
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1980
- Tongue
- English
- Weight
- 318 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0022-152X
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📜 SIMILAR VOLUMES
## Abstract magnified image A relatively short and efficient method for the utilization of 4,6‐dichloro‐2‐methylthio‐5‐nitropyrimidine (**1**) in the synthesis of the poly substituted pyrrolo[3,2‐__d__]pyrimidin‐7‐one 5‐oxides (**6a**‐g) is reported. Some new 4‐substituted 6‐chloro‐2‐methylthio‐5‐
## Abstract The reaction of 1‐aryl‐3‐(dimethylamino)‐1‐propanones 1 with one equivalent of 4,5‐diamino‐1__H__‐pyrimidin‐6‐ones 2, in acidic medium, leads to the formation of 4‐aryl‐2,3,6,7‐tetrahydro‐1__H__‐pyrimido[4,5‐__b__]‐[1,4]diazepin‐6‐ones 3. The structure elucidation of the products is bas