✦ LIBER ✦

2-{2-[3-(Pyridin-3-yloxy)phenyl]-2H-tetrazol-5-yl}pyridine: A Highly Potent, Orally Active, Metabotropic Glutamate Subtype 5 (mGlu5) Receptor Antagonist.

✍ Scribed by Dehua Huang; Steve F. Poon; Deborah F. Chapman; Janice Chung; Merryl Cramer; Thomas S. Reger; Jeffrey R. Roppe; Lida Tehrani; Nicholas D. P. Cosford; Nicholas D. Smith

Publisher: John Wiley and Sons
Year: 2005
Weight: 13 KB
Volume: 36
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200514229

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

3-[3-Fluoro-5-(5-pyridin-2-yl-2H-tetrazo

3-[3-Fluoro-5-(5-pyridin-2-yl-2H-tetrazol-2-yl)phenyl] -4-methylpyridine: A Highly Potent and Orally Bioavailable Metabotropic Glutamate Subtype 5 (mGlu5) Receptor Antagonist.

✍ Steve F. Poon; Brian W. Eastman; Deborah F. Chapman; Janice Chung; Merryl Cramer 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 9 KB

3-[Substituted]-5-(5-pyridin-2-yl-2H-tet

3-[Substituted]-5-(5-pyridin-2-yl-2H-tetrazol-2-yl)benzonitriles: Identification of Highly Potent and Selective Metabotropic Glutamate Subtype 5 Receptor Antagonists.

✍ Lida R. Tehrani; Nicholas D. Smith; Dehua Huang; Steve F. Poon; Jeffrey R. Roppe 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 9 KB

5-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-2

5-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-2,3′-bipyridine: A Highly Potent, Orally Active Metabotropic Glutamate Subtype 5 (mGlu5) Receptor Antagonist with Anxiolytic Activity.

✍ Jeffrey R. Roppe; et al. et al. 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 18 KB

Discovery of Highly Potent, Selective, O

Discovery of Highly Potent, Selective, Orally Bioavailable, Metabotropic Glutamate Subtype 5 (mGlu5) Receptor Antagonists Devoid of Cytochrome P450 1A2 Inhibitory Activity.

✍ Nicholas D. Smith; et al. et al. 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 12 KB 👁 1 views

Discovery of a Potent, Selective and Ora

Discovery of a Potent, Selective and Orally Active Canine COX-2 Inhibitor, 2-(3-Difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl-pyridine.

✍ Jin Li; et al. et al. 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 104 KB 👁 2 views

## Abstract For Abstract see ChemInform Abstract in Full Text.

9H-Xanthene-9-carboxylic Acid [1,2,4]Oxa

9H-Xanthene-9-carboxylic Acid [1,2,4]Oxadiazol-3-yl- and (2H-Tetrazol-5-yl)-amides as Potent, Orally Available mGlu1 Receptor Enhancers.

✍ Eric Vieira; Joerg Huwyler; Synese Jolidon; Frederic Knoflach; Vincent Mutel; Ju 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 13 KB