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1H NMR spectral simplification with achiral and chiral lanthanide shift reagents — IV. Thiopental and barbiturate analogues

✍ Scribed by Suzanne Thomson Eberhart; Alexander Hatzis; Jose Jimenez; Robert Rothchild; Paul Simons


Book ID
103910855
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
917 KB
Volume
5
Category
Article
ISSN
0731-7085

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1H NMR studies of drugs with achiral and
✍ Bridget Byrne; Robert Rothchild 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 163 KB 👁 2 views

The anticonvulsant pheneturide, PNT, has been studied by 300 MHz 1H NMR in CDCl3 at ambient temperatures with the achiral lanthanide shift reagent (LSR) Eu(FOD)3, and with the chiral LSR, Eu(HFC)3. Both LSRs produced spectral simplification of the aryl proton signal region, and substantial lanthanid