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1H NMR spectral simplification with achiral and chiral lanthanide shift reagents. Tranylcypromine, trans-2-phenylcyclopropanamine

✍ Scribed by Alexander Hatzis; Robert Rothchild


Book ID
103910804
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
640 KB
Volume
4
Category
Article
ISSN
0731-7085

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1H NMR studies of drugs with achiral and
✍ Bridget Byrne; Robert Rothchild πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 163 KB πŸ‘ 2 views

The anticonvulsant pheneturide, PNT, has been studied by 300 MHz 1H NMR in CDCl3 at ambient temperatures with the achiral lanthanide shift reagent (LSR) Eu(FOD)3, and with the chiral LSR, Eu(HFC)3. Both LSRs produced spectral simplification of the aryl proton signal region, and substantial lanthanid