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1 H NMR Spectral Simplification with Achiral and Chiral Lanthanide Shift Reagents. Mexiletine

✍ Scribed by Aboul-Enein, Hassan Y.; Médonné, Simonique; Rothchild, Robert


Book ID
126654904
Publisher
Taylor and Francis Group
Year
1991
Tongue
English
Weight
603 KB
Volume
24
Category
Article
ISSN
0038-7010

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1H NMR studies of drugs with achiral and
✍ Bridget Byrne; Robert Rothchild 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 163 KB 👁 2 views

The anticonvulsant pheneturide, PNT, has been studied by 300 MHz 1H NMR in CDCl3 at ambient temperatures with the achiral lanthanide shift reagent (LSR) Eu(FOD)3, and with the chiral LSR, Eu(HFC)3. Both LSRs produced spectral simplification of the aryl proton signal region, and substantial lanthanid