𝔖 Bobbio Scriptorium
✦   LIBER   ✦

1H n.m.r. investigation on the site of hydration in the asymmetric diazanaphthalenes

✍ Scribed by Peter van de Weijer; Douwe van der Meer

Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
311 KB
Volume
9
Category
Article
ISSN
0749-1581

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The site of hydration for 1,6‐ and 1,7‐naphthyridine has been determined by specific line broadening in the ^1^H n.m.r. spectra on the addition of water. The site of hydration appears to be the same as the site of protonation (β‐nitrogen atom). The site of hydration in quinazoline has been shown to be the α‐nitrogen atom. This strongly indicates that the site of protonation in this compound will also be at that nitrogen.

📜 SIMILAR VOLUMES

Carbon-13 n.m.r. investigation on the ni
Carbon-13 n.m.r. investigation on the nitrogen methylation of the mono- and diazanaphthalenes
✍ Peter van de Weijer; (the late) Chandra Mohan; Dirk M. W. van den Ham 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 394 KB

## Abstract The ^13^C n.m.r. spectra of the __N__‐methylated mono‐ and diazanaphthalenes have been recorded and analysed. It has been shown that __N__‐methylation as well as __N__‐protonation in cinnoline occur predominantly at the β‐nitrogen atom. __N__‐methylation and __N__‐protonation show a sim

13C n.m.r. investigation on the first an
13C n.m.r. investigation on the first and second nitrogen protonation in the diazanaphthalenes
✍ Peter van de Weijer; Dirk M. W. van den Ham; Douwe van der Meer 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 403 KB

## Abstract The ^13^C chemical shifts of the diazanaphthalenes have been recorded as a function of the pH value, providing classical titration curves. From these curves the p__K__~1~ and p__K__~2~ values have been determined taking into account the activity coefficients. The changes in ^13^C chemic

Diazanaphthalenes: A 13C NMR investigati
Diazanaphthalenes: A 13C NMR investigation on the site of protonation and pKa values
✍ Peter van de Weijer; Hans Thijsse; Douwe van der Meer 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 English ⚖ 472 KB

## Abstract The pH dependence of the ^13^C chemical shifts (δ) of the diazanaphthalenes has been recorded. From this dependence the p__K__~__a__~ values have been determined using the Henderson‐Hasselbach equation. The change in ^13^C chemical shifts under the influence of nitrogen protonation (Δδ)

N.m.r. studies in the heterocyclic serie
N.m.r. studies in the heterocyclic series: XVI—determination of the structure of 3-azidoindazole by 1H and 13C n.m.r. spectroscopy
✍ Alain Fruchier; Ermitas Alcalde; José Elguero 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 155 KB 👁 1 views

## Abstract The 1‐NH structure for 3‐azidoindazole has been demonstrated by the observation of ^1^H^1^H and ^13^C^1^H couplings involving the hydrogen atom attached to nitrogen. A comparison between 3‐azidoindazole and indazole shows that both compounds have the same tautomeric structure.

The effect of O-methylation on chemical
The effect of O-methylation on chemical shifts in the 1H- and 13C-n.m.r. spectra of cyclic polyols
✍ Stephen J. Angyal; Léon Odier 📂 Article 📅 1983 🏛 Elsevier Science 🌐 English ⚖ 361 KB

The 'H-and "C-n.m.r. spectra of seven in&lo1 methyl ethers were recorded and assigned. They were classified into five types, and the effect of 0methyl&ion on the chemical shifts of each type is discussed. NOTE ADDED IN PROOF Type F, not encountered in our work, occurs in 1,6-anhydro-3-O-methyl-& D

Effect of substituents on the 1H n.m.r.
Effect of substituents on the 1H n.m.r. spectra of para-disubstituted benzenes. A graphical aid in the correct assignment of chemical shifts
✍ Miroslav Holík 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 207 KB

## Abstract In __para__‐disubstituted benzenes, the effect of one substituent is transferred to the other composite substituent group and its decreased influence on the __ortho__ and __meta__ protons is reflected in their chemical shifts. A graphical presentation of this linear non‐additive depende