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191: The role of human CYP2B6 polymorphism in the bioactivation of cyclophosphamide using cDNA expressed enzymes

✍ Scribed by P. Afsharian; Y. Terelius; M. Hidestrand; M. Ingelman-Sundberg; M. Hassan; S. Lundgren


Book ID
116279372
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
63 KB
Volume
13
Category
Article
ISSN
1083-8791

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## Abstract A human lymphoblastoid cell line stably expressing a human cytochrome P4501A2 cDNA was developed. This recombinant cell line displayed P4501A2 protein and estradiol2‐hydroxylase activity, neither of which was detected in the parental cell line. The recombinant cell line was also approxi