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184 Reduced rho-kinase expression is involved in vascular hypocontractility in rats with secondary biliary cirrhosis

✍ Scribed by M. Hennenberg; K. Jochem; M. Schepke; T. Sauerbruch; J. Heller

Book ID
117373014
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
62 KB
Volume
40
Category
Article
ISSN
0168-8278

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Defective endothelial nitric oxide synth
Defective endothelial nitric oxide synthase signaling is mediated by rho-kinase activation in rats with secondary biliary cirrhosis
✍ Go Anegawa; Hirofumi Kawanaka; Daisuke Yoshida; Kozo Konishi; Shohei Yamaguchi; πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 805 KB

In liver cirrhosis, down-regulation of endothelial nitric oxide synthase (eNOS) has been implicated as a cause of increased intrahepatic resistance. We investigated whether Rho-kinase activation is one of the molecular mechanisms involved in defective eNOS signaling in secondary biliary cirrhosis. L