(+)-(18-Crown-6)-2,3,11,12-Tetracarboxylic Acid and Its Ytterbium(III) Complex as Chiral NMR Discriminating Agents
β Scribed by Wenzel, Thomas J.; Thurston, Jolene E.
- Book ID
- 120545627
- Publisher
- American Chemical Society
- Year
- 2000
- Tongue
- English
- Weight
- 134 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0022-3263
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## Abstract Chiral discrimination studies using (+)β(18βcrownβ6)β2,3,11,12βtetracarboxylic acid (18βCβ6βTA) as a chiral selector were performed by highβperformance liquid chromatography (HPLC) and NMR spectroscopy. The enantiomers of alanine (Ala) or alanine methyl ester (AlaβME) were well separate
## Abstract Enantiomeric discrimination is observed in the ^1^H and ^13^C NMR spectra of secondary and tertiary amines in the presence of (β)β(18βcrownβ6)β2,3,11,12βtetracarboxylic acid (**1**). Nonequivalence of the resonances of prochiral nuclei in primary and secondary amines is also observed wh