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163. Remission induction therapy of refractory acute promyelocytic leukemia (APL) with all-trans retinoic acid (ATRA)

โœ Scribed by Ohno, R; Yoshida, H; Naoe, T; Ohshima, T; Dohi, H; Endo, N; Fujimoto, T; Kobayashi, T; Hiraoka, A; Kodera, Y


Book ID
123068193
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
131 KB
Volume
46
Category
Article
ISSN
0753-3322

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๐Ÿ“œ SIMILAR VOLUMES


ALL-TRANS RETINOIC ACID (ATRA) IN THE TR
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Acute promyelocytic leukemia is characterized by the reciprocal translocation of chromosomes 15 and 17. All-trans retinoic acid (ATRA) efficiently induces differentiation of the abnormal promyelocytes. In this study, we had used ATRA as the primary induction therapy for 17 newly diagnosed patients,

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โœ Advani, Suresh H.; Nair, Reena; Bapna, Ajay; Gladstone, Betty; Kadam, Pratibha; ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 61 KB ๐Ÿ‘ 2 views

This study was conducted to compare the results of treatment of acute promyelocytic leukemia (APL) with all-trans retinoic acid alone (ATRA) or a combination therapy of ATRA followed by chemotherapy. Forty-three patients treated between February 1992 and February 1996 were included in this study. Ei