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162 Urinary Excretion of Organic Anions and Cations in Bile Duct-Ligated Rats

✍ Scribed by Takada, Y


Book ID
122379841
Publisher
Springer-Verlag
Year
2003
Tongue
English
Weight
63 KB
Volume
7
Category
Article
ISSN
1091-255X

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✍ Nimish Vakil; Anil Sharma; Yoram Yagil πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 662 KB

In an earlier study we showed that bile duct-ligated rats were highly susceptible to gentamicin nephrotoxicity and that oral calcium administration had a pronounced protective effect. The mechanism by which this occurs is unclear. Because cations compete with gentamicin for tubule binding sites, it