The regulatory responses of bile acid (BA) transport in the terminal ileum to perturbations in BA homeostasis are complex, and conflicting results have been reported by different investigators. These studies were designed to examine the response of this system to a reduction in ileal bile salt conce
✦ LIBER ✦
Urinary excretion of lithocholic acid and its conjugates by the bile duct–ligated rat
✍ Scribed by Joanna M. Little; Piotr Zimniak; Anna Radominska; Roger Lester; Paul Lehman
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 758 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0270-9139
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## Abstract The heterocyclic amine 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐__b__]pyridine (PhIP) is a recognized mutagen and carcinogen in the colon and prostate of male rats and in the mammary gland of female rats. In the current study, we examined the mutagenicity of PhIP in the kidney of male and f