1,6-addition of organocopper reagents to 3-ethynyl-2-methyl-2-cyclopentenone
โ Scribed by Martin Hulce
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 199 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
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## s-412 % Gotebofg, swedell Organ~pper xeagenU of diffenmt compositions are highly useful tools in organic synthesis for the formation of new carbon -carbon bonds.1 Cons&able effort has been spent in attempts to achieve high stereoselectivityinthebolKlformation. Enan~vityviachiralauxilipritsindl
1.6 addition of carbanionic reagents to bicycllc dtenone I requires anlonic activation : according to the acidity ,of the corresponding carbon acids, good yields in 7d -adducts can be obtained either in THF-HMPA with nBuLi or tBuOK as bases or under solid-liquid phase transfer catalysis.