Synthesis of 15N-labelled nornicotine an
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Giang Vo-Thanh; François-Xavier Felpin; Gilbert Nourrisson; Michel Trierweiler;
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Article
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2001
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John Wiley and Sons
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French
β 103 KB
π 1 views
## Abstract The synthesis of ^15^Nβlabelled nornicotine **2** and ^15^Nβlabelled nicotine **1** is described via the reductive aminocyclization of a 1,4βketoaldehyde with a corresponding amine in the presence of sodium cyanoborohydride. Yields of 30% and 26%, respectively, were obtained from 3βbrom