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158 cytokines control CD4+ CD25+ Foxp3+ regulatory T-cell survival and their mechanism of suppression

✍ Scribed by Pushpa Pandiyan; Michael Lenardo


Book ID
116398430
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
45 KB
Volume
43
Category
Article
ISSN
1043-4666

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## Abstract Interleukin‐2 (IL‐2) treatment is currently used to enhance T cell‐mediated immune responses against tumors or in viral infections. At the same time, IL‐2 is essential for the peripheral homeostasis of CD4^+^CD25^+^Foxp3^+^ regulatory T cells (Treg). In our study, we show that IL‐2 is a