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F.89. Rapid Suppression of Activation Markers and Cytokine Secretion in Human CD4+CD25- T Cells by Cord Blood Derived CD4+CD25+FOXP3+ T Regulatory Cells

✍ Scribed by Liping Jiang; Stephanie Anover-Sombke; Hans Ochs; Troy Torgerson


Book ID
113540344
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
36 KB
Volume
127
Category
Article
ISSN
1090-2341

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## Abstract Interleukin‐2 (IL‐2) treatment is currently used to enhance T cell‐mediated immune responses against tumors or in viral infections. At the same time, IL‐2 is essential for the peripheral homeostasis of CD4^+^CD25^+^Foxp3^+^ regulatory T cells (Treg). In our study, we show that IL‐2 is a