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151 Mutant P53 Gain of Function Via P63

✍ Scribed by M. Stindt; P. Muller; K.H. Vousden


Book ID
117662688
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
72 KB
Volume
48
Category
Article
ISSN
0959-8049

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## Abstract Cancer might result from both the aberrant activation of genes, whose physiological tuning is essential for the life of a normal cell, and the inactivation of tumor suppressor genes, whose main job is to preserve the integrity of cell genome. Among the latter, p53 is considered a key tu