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Mutant p53 gain of function: The NF-Y connection

✍ Scribed by Melissa J. Peart; Carol Prives


Book ID
113523708
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
260 KB
Volume
10
Category
Article
ISSN
1535-6108

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## Abstract Cancer might result from both the aberrant activation of genes, whose physiological tuning is essential for the life of a normal cell, and the inactivation of tumor suppressor genes, whose main job is to preserve the integrity of cell genome. Among the latter, p53 is considered a key tu