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15 Optimization of testing times and critical values in sequential equivalence testing

✍ Scribed by Hans-Helge Müller; Helmut Schäfer


Book ID
114187259
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
63 KB
Volume
18
Category
Article
ISSN
0197-2456

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Optimization of testing times and critic
✍ Hans-Helge Müller; Helmut Schäfer 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 167 KB 👁 1 views

In long-term clinical trials, interim analyses are planned to reduce the number of patients needed. To meet this issue in a practical way, group sequential designs are used. Most of these trials are conducted with the objective of demonstrating di!erences in e$cacy of treatments, for example, to sho