Optimization of testing times and critic
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Hans-Helge Müller; Helmut Schäfer
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Article
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1999
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John Wiley and Sons
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English
⚖ 167 KB
👁 1 views
In long-term clinical trials, interim analyses are planned to reduce the number of patients needed. To meet this issue in a practical way, group sequential designs are used. Most of these trials are conducted with the objective of demonstrating di!erences in e$cacy of treatments, for example, to sho