15-deoxy-Δ12,14-prostaglandin J2, a ligand for peroxisome proliferators-activated receptor-γ, induces apoptosis in human hepatoma cells
✍ Scribed by Masataka Date; Kazuhide Fukuchi; Shosuke Morita; Hiroshi Takahashi; Kiyoshi Ohura
- Book ID
- 111237205
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 239 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0106-9543
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## Abstract 15‐deoxy‐Δ^12,14^ prostaglandin J~2~ (15dPGJ~2~), a peroxisome proliferator‐activated receptor gamma (PPARγ) ligand, induced synergistic stimulation of DNA synthesis in the presence of phorbol dibutyrate (PDB) in Swiss 3T3 cells. This effect was dose‐dependent and the maximum response w