15-Deoxy Δ12,14-prostaglandin J2 suppresses transcription by promoter 3 of the human thromboxane A2 receptor gene through peroxisome proliferator-activated receptor γ in human erythroleukemia cells
✍ Scribed by Adrian T. Coyle; Martina B. O'Keeffe; B. Therese Kinsella
- Book ID
- 111310190
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 511 KB
- Volume
- 272
- Category
- Article
- ISSN
- 1432-1327
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## Abstract 15‐deoxy‐Δ^12,14^ prostaglandin J~2~ (15dPGJ~2~), a peroxisome proliferator‐activated receptor gamma (PPARγ) ligand, induced synergistic stimulation of DNA synthesis in the presence of phorbol dibutyrate (PDB) in Swiss 3T3 cells. This effect was dose‐dependent and the maximum response w