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14q translocations, having a break point at 14q13, in lymphoid malignancy

✍ Scribed by Shirou Fukuhara; Yoshimi Ueshima; Shigeru Shirakawa; Haruto Uchino; Shigeru Morikawa

Publisher: John Wiley and Sons
Year: 1979
Tongue: French
Weight: 861 KB
Volume: 24
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910240606

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

In three patients with non‐Hodgkin lymphomas and in one cell line (HPL‐Hod) derived from pleural effusion cells of a patient with Hodgkin's disease, rearrangements of the long arm of chromosome No. 14(14q) were observed. These rearrangements appeared to be consistently associated with a 14q translocation, suggestive of occurrence of a break at 14q13. The translocation in an individual case could occur with 1p, 2q, 4q, and another 14q. A 14q13 translocation may be comparable with a 14q32 translocation, which has often been observed in various types of lymphoid malignancy.

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