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131-metaiodobenzylguanedine therapy of neuroblastoma in childhood

✍ Scribed by D. Schwabe; St. Sahm; V. Gerein; J. Happ; H. Kropp-v. Rabenau; F. Maul; R. P. Baum; K. Manegold; C. Nitz; G. Hör; B. Kornhuber


Book ID
104903409
Publisher
Springer
Year
1987
Tongue
English
Weight
927 KB
Volume
146
Category
Article
ISSN
0340-6997

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I MIBG has been used as palliative treatment of neuroblastoma patients with recurrent or persistent disease who failed other modalities of treatment. Since the results were promising, the concept arose of using it in conjunction with other modalities, either as an up-front treatment or as combinatio

Considerations on131I-metaiodobenzylguan
✍ Sanguineti, Michele 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 289 KB

Six children affected by neuroblastoma at stages III and IV were treated with high-specific-activity 131I-metaiodobenzylguanidine (MIBG). After 131I-MIBG treatment three patients died at 12, 10, and 12 weeks, respectively; the other three were still living at 21, 16, and 24 weeks, respectively. Alth