Toxicity of upfront131I-metaiodobenzylguanidine (131I-MIBG) therapy in newly diagnosed neuroblastoma patients: a retrospective analysis
β Scribed by Bleeker, Gitta; Schoot, Reineke A.; Caron, Huib N.; Kraker, Jan; Hoefnagel, Cees A.; Eck, Berthe L.; Tytgat, Godelieve A.
- Book ID
- 121619336
- Publisher
- Springer
- Year
- 2013
- Tongue
- English
- Weight
- 143 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0340-6997
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Effects of high activities of I 131 meta-iodobenzylguanidine (mIBG) were evaluated in nine children with advanced neuroblastoma. All patients had been previously heavily treated and had either primarily refractory disease or resistant relapse. Twenty-two doses of mIBG labeled with 1.3 to 4 GBq (35-1
Our experience in scintigraphic diagnosis using 123I/131I-metaiodobenzylguanidine (MIBG) on 37 children with neuroblastomas stage III-IV is reported and discussed, together with the results obtained by other authors on MIBG diagnosis at the International Workshop of Pediatric Oncology held in Rome i