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1,3-Dipolar cycloaddition reactions of 2-phenyl-4-arylidene-5(4H)-oxazolones with nitrile oxides

โœ Scribed by N. G. Argyropoulos; E. Coutouli-Argyropoulou


Book ID
112127618
Publisher
Journal of Heterocyclic Chemistry
Year
1984
Tongue
English
Weight
233 KB
Volume
21
Category
Article
ISSN
0022-152X

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## Abstract Nitrile oxides 2a, b and nitrile imines 2cโ€“e are added to the C ๏ฃพ C bond of 4โ€arylideneโ€2โ€phenylโ€5(4__H__)โ€thiazolones 1 to afford spiroโ€isoxazolines 3aโ€“d and spiroโ€pyrazolines 3eโ€“j, respectively. The cycloaddition reactions are regioselective and only one of the two possible regioisome

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The use of different aluminum derivatives in the reaction between cyclopentadiene and (Z)-2-phenyl-4-arylidene-5(4H)oxazolones, and in particular the use of different equivalents of the reagent, allows the modulation of the synthesis of the norbornane skeleton by a [4+2] cycloaddition or the more in